It took scientists a decade and cost about $1 billion to sequence the first human genome. Ten years later, it can be done in three days for about $1,000. Drug development, too, has become much more efficient, as researchers use human genetics to increase their odds for success.
It's been a rough six years for Mark Fetting, and he's only been CEO for four of them. When the 57-year-old took the reins of Baltimore-based Legg Mason  in January 2008, he knew he was inheriting a handful of not-insignificant problems stemming from swallowing a difficult acquisition, the faltering of a high-profile fund, and a cultural